Research and Studies
Published research regarding the role of omega-3 and vitamin E supplementation in children: scientists proclaim omega-3 supplementation effective in learning.
A study published in the July/August 2009 journal Alternative Therapies in Health and Medicine describes the benefits noted in 97% of participants while taking a nutritional combination comprised of omega-3 and vitamin E.
To learn more about this study, click here.
The Oxford-Durham Schools Trials
Initial Trial results summary:
The most comprehensive and thorough trial yet of how omega-3 may be applied in the classroom. This trial was run by the British Government through its Durham Education Authority. During the course of 2002, more than 100 children at 12 different schools were daily given either active or placebo capsules in a double-blind, randomized format. More than 12,000 assessments were undertaken in the course of the year. The first results were published in the American Journal Pediatrics and showed very significant improvements for active treatment versus placebo in reading, spelling, and behavior over 3 months of treatment in parallel groups. After the crossover, similar changes were seen in the placebo-active group, whereas children continuing with active treatment maintained or improved their progress.
The most comprehensive and thorough trial yet of how omega-3 may be applied in the classroom. This trial was run by the British Government through its Durham Education Authority. During the course of 2002, more than 100 children at 12 different schools were daily given either active or placebo capsules in a double-blind, randomized format. More than 12,000 assessments were undertaken in the course of the year. The first results were published in the American Journal Pediatrics and showed very significant improvements for active treatment versus placebo in reading, spelling, and behavior over 3 months of treatment in parallel groups. After the crossover, similar changes were seen in the placebo-active group, whereas children continuing with active treatment maintained or improved their progress.
“The response has been very encouraging. In very broad terms, we saw that up to 40% of children in the trial showed dramatic improvements. In some individual cases, we saw reading age gains of between 18 months and 4 years, and attention gains of as much as 400%.”
—Dr. Madeleine Portwood, Senior Educational Psychologist
Additional References:
Amminger GP, Berger GE, et al. Biol Psychiatry, 2007;61(4):551-553
Agin M, (FAND-2001); 2001; Oxford, United Kingdom.
Booth SL, Golly I, et al. Am J Clin Nutr, 2004;80(1):143-148
Chauhan A, Chauhan V. Pathophysiology, 2006 Aug;13(3):171-81
Cyhlarova E, Bell JG, et al. Eur Neuropsychopharml, 2007; 17: 116-121
Garber AK, Binkley NC, et al. J. Nutr, 1999; 129: 1201–1203
Gil A, Ramirez M, Gil M. Eur J Clin Nutr, 2003;57 Suppl 1:S31-34
Handelman GJ, Machlin LJ, et al. J Nutrition, 1985; 115(6): 807-813
Hadjivassiliou M, Grunewald RA, Davies-Jones GA. J Neurol Neurosurg Psychiatry. 2002; 72: 560-563
Hathcock JN, Azzi A, et al. Am J Clin Nutr, 2005 Apr;81(4):736-745
Hallert C, Grant C, et al. Aliment Pharmacol Ther, 2002; 16:1333-1339
Jiang Q, Christen S, et al. Am J Clin Nutr, 2001;74(6):714-722
Kleopa KA, Kyriacou K, et al. Muscle Nerve, 2005;31(2):260-265
Nakamura MT, Cho HP, et al. Lipids, 2001 Sep;36(9):961-964
Morris CR, Geng L, Agin MC. Pediatric Academy Societies, 2008.
Morris CR, Agin MC. Pediatric Academy Societies, 2007. Late Breaker Abstract Presentation # 5570.8.
Roth LL. (FAND-2001) Oxford, United Kingdom, 2001
Richardson AJ. Int Rev Psychiatry, 2006;18(2):155-172
Richardson AJ, Montgomery P. Pediatrics, 2005;115 (5):1360-1366
Richardson AJ, Puri BK. Prog Neuropsychopharm Biol Psychiatry, 2002; 26(2):233-239
Richardson AJ. Prostaglandins Leukot Essent Fatty Acids. 2004;70(4):383-390
Richardson AJ. Lipids. 2004;39(12):1215-1222
Richardson AJ, Ross MA. Prostaglandins Leukot Essent Fatty Acids, 2000; 63: 1-9
Roberts LJ, 2nd, Oates JA, et al. Free Radic Biol Med, 2007;43(10):1388-1393
Sokol RJ. Adv Pediatr, 1990;37:119-148
Sokol RJ. Free Radic Biol Med. 1989;6(2):189-207
Sinn N, Bryan J. J Dev Behav Pediatr, 2007; 28(2): 82-91
Stevens L, Zhang W, et al. Lipids, 2003; 38(10): 1007-1021
Stevens LJ, Zentall SS, et al. Physiol Behav, 1996; 59(4-5): 915-920
Taylor KE, Higgins CJ, et al. Prostaglandins Leukot Essent Fatty Acids, 2000;63:75-78
Traber MG, Packer L. Am J Clin Nutr, 1995; 62:1501S-1509S
Traber MG. Curr Opin Gastroenterol. 2005; 21: 223-227
Traber MG. Br J Nutr. 2006;96 Suppl 1:S34-37
Uauy R, Hoffman DR, et al. J Pediatr, 1994; 124: 612-620
Valk EE, Hornstra G. Int J Vitam Nutr Res, 2000;70(2):31-42
Vancassel S, Durand G, et al. Prostaglandins Leukot Essent Fatty Acids, 2001;65(1):1-7
Yehuda S, Rabinovitz S, Mostofsky DI. J Neurosci Res, 1999; 56(6): 565-570
Young G, Conquer J. Reprod Nutr Dev, 2005; 45: 1-28
